Linear energy transfer incorporated intensity modulated proton therapy optimization
نویسندگان
چکیده
منابع مشابه
Intensity modulated proton therapy.
Intensity modulated proton therapy (IMPT) implies the electromagnetic spatial control of well-circumscribed "pencil beams" of protons of variable energy and intensity. Proton pencil beams take advantage of the charged-particle Bragg peak-the characteristic peak of dose at the end of range-combined with the modulation of pencil beam variables to create target-local modulations in dose that achie...
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Radiation therapy is a non-invasive treatment modality for cancer patients. Radiation therapy treatment planning for cancer patients provides many challenging optimization problems. Various variables of a treatment plan need to be optimized so that the resulting plan can kill all cancerous cells while minimizing damage on the patient’s normal tissues. Intensity modulated proton therapy (IMPT) h...
متن کاملPrioritized efficiency optimization for intensity modulated proton therapy.
A high dosimetric quality and short treatment time are major goals in radiotherapy planning. Intensity modulated proton therapy (IMPT) plans obtain dose distributions of great conformity but often result in long delivery times which are typically not incorporated into the optimization process. We present an algorithm to optimize delivery efficiency of IMPT plans while maintaining plan quality, ...
متن کاملProton-Beam vs Intensity-Modulated Radiation Therapy
June 01, 2008 External-beam radiation is a highly effective curative treatment option for men with localized prostate cancer.[1,2] Over the past several decades, efforts have been made to improve the “therapeutic ratio” of radiation by increasing dose to improve cure rates without causing a substantial increase in side effects. Due to its potential to create superior dose distributions, proton ...
متن کاملA critical evaluation of worst case optimization methods for robust intensity-modulated proton therapy planning.
PURPOSE To critically evaluate and compare three worst case optimization methods that have been previously employed to generate intensity-modulated proton therapy treatment plans that are robust against systematic errors. The goal of the evaluation is to identify circumstances when the methods behave differently and to describe the mechanism behind the differences when they occur. METHODS The...
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ژورنال
عنوان ژورنال: Physics in Medicine & Biology
سال: 2017
ISSN: 1361-6560
DOI: 10.1088/1361-6560/aa9a2e